ESTABLISHING CORRELATION OF pH WITH VARIOUS PHYSIOCHEMICAL AND TRADITIONAL PARAMETERS OF ACID BASE BALANCE: A CROSS-SECTIONAL STUDY

OBJECTIVE: To evaluate the effectiveness of Physiochemical versus traditional approach in diagnosing acid-base disorders (ABD). METHODS: This cross-sectional observational study was conducted on 212 patients, admitted during January to June 2020, intensive care unit Rehman Medical Institute, Peshawar, Pakistan. Samples were obtained from these patients for pH, PCO2, HCO3, lactate, Na, K and Cl processed Cobas ABG analyzer b 221. Ca, Mg, albumin phosphate analyzed Cobas-601. Data assess association among different parameters approach. RESULTS: Males predominant total cohort group (n=125/212; 59%) as well metabolic subgroup (n=109/184; 59%). Mean age males females 55.01±11.80 years 54.99±14.76 respectively. pH showed a strong negative correlation with PO4 (p-value=0.001) (rs 0.238) subjects no significant (p=0.005) -.206) physiochemical In acid base parameters, Standard Base Excess (SBE) positive (p=0.001) 0.413 rs 0.567) pCO2 strongest (p value 0.001) -0.721 -0.673) both subgroup. HCO3 (p=0.003) 0.221) AG (p=0.024) -0.167) CONCLUSION: No between blood found adults. Traditional is simplest, most rigorous, useful ABD.